The advent of BRAF inhibitors and immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of melanoma patients. However, melanoma subtypes such as limbal, mucosal, and uveal melanomas are less responsive to these therapies than cutaneous melanomas, and new therapeutic agents are urgently needed for treatment-resistant patients. Antibody-drug conjugates (ADCs) achieve targeted killing of tumor cells
The biological landscape inside tissues is remarkably complex. Cells are not only diverse in type and function but are also spatially arranged in highly organized patterns that dictate their interactions and behaviors. While traditional single-cell technologies provide valuable insights into cellular states, they often miss the spatial context that defines how cells function in real
Throughout human history, the immune system has been our greatest defense against viral threats. As a cornerstone of the innate immune system, Natural Killer (NK) cells have emerged as a game-changer in antiviral research due to their unique ability to recognize and eliminate infected cells without prior exposure. From COVID-19 to influenza and HIV, NK
Next-generation sequencing (NGS) has become a pivotal technology in cancer diagnostics, offering exceptional sensitivity, throughput, and cost efficiency. By enabling comprehensive genomic analysis, NGS has transformed how cancer is understood and detected. Advanced platforms now integrate technologies such as Whole Exome Sequencing (WES) and Circle-Seq-based eccDNA identification, providing researchers with powerful tools to unravel the complexity
Don’t Miss Out: August 22, 12 PM EDT! Mark your calendar now—August 22, 2025 at 12 PM EDT—for an exclusive live webinar hosted by Creative Biolabs, spotlighting the revolutionary tumoroid-on-a-chip technology for cancer immunotherapy research. This highly anticipated session, titled “Tumoroid-on-a-Chip as a Physiologically Relevant Model for Immunotherapy,” will be led by Dr. Mohsen Akbari,